One-Step Preparation of Poly-Lactic-Co-Glycolic-Acid Microparticles to Prevent the Initial Burst Release of Encapsulated Water-Soluble Proteins
نویسندگان
چکیده
منابع مشابه
The visualisation of vitreous using surface modified poly(lactic-co-glycolic acid) microparticles
AIMS To demonstrate the potential use of in vitro poly(lactic-co-glycolic acid) (PLGA) microparticles in comparison with triamcinolone suspension to aid visualisation of vitreous during anterior and posterior vitrectomy. METHODS PLGA microparticles (diameter 10-60 microm) were fabricated using single and/or double emulsion technique(s) and used untreated or following the surface adsorption of a...
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The CD95/CD95L receptor-ligand system is mainly recognised in the induction of apoptosis. However, it has also been shown that CD95L is over-expressed in many cancer types where it modulates immune-evasion and together with its receptor CD95 promotes tumour growth. Here, we show that CD95 surface modification of relatively large microparticles >0.5 μm in diameter, including those made from biod...
متن کاملControl of Alginate Core Size in Alginate-Poly (Lactic-Co-Glycolic) Acid Microparticles
Core-shell alginate-poly (lactic-co-glycolic) acid (PLGA) microparticles are potential candidates to improve hydrophilic drug loading while facilitating controlled release. This report studies the influence of the alginate core size on the drug release profile of alginate-PLGA microparticles and its size. Microparticles are synthesized through double-emulsion fabrication via a concurrent ionotr...
متن کاملPreparation of antibacterial electrospun Poly lactic-co–glycolic acid nanofibers containing Hypericum Perforatum with bedsore healing property and evaluation of its drug release performance
Skin drug delivery systems with controlled release are suitable means for the local transfer of pharmaceutical compounds to the damaged and healthy layers of skin. Nanofibrous membrane prepares uniform moisture in the wound environment with less accumulation of fluid secretion due to its variable pore size. Electrospinning takes advantage of using herbal extracts in the form of electrospun nano...
متن کاملPreparation of antibacterial electrospun Poly lactic-co–glycolic acid nanofibers containing Hypericum Perforatum with bedsore healing property and evaluation of its drug release performance
Skin drug delivery systems with controlled release are suitable means for the local transfer of pharmaceutical compounds to the damaged and healthy layers of skin. Nanofibrous membrane prepares uniform moisture in the wound environment with less accumulation of fluid secretion due to its variable pore size. Electrospinning takes advantage of using herbal extracts in the form of electrospun nano...
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ژورنال
عنوان ژورنال: Pharmacology & Pharmacy
سال: 2013
ISSN: 2157-9423,2157-9431
DOI: 10.4236/pp.2013.48083